 | |
| 臨床資料 | |
|---|---|
| 商品名 | Alizin |
| 其他名稱 | 安哥司酮、RU-46534、RU-534 |
| 藥物類別 | 抗孕激素、抗糖皮质激素 |
| ATC碼 | |
| 识别信息 | |
| |
| CAS号 | 124478-60-0 |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.211.372 |
| 化学信息 | |
| 化学式 | C29H37NO2 |
| 摩尔质量 | 431.62 g·mol−1 |
| 3D模型（JSmol） | |
| |
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阿来司酮（INN：aglepristone；开发代号：RU-46534、RU-534），或译安哥司酮，是一种与米非司酮相关的合成类甾体抗孕激素，由维克在几个欧洲国家销售，用作兽药。[1][2][3]它专门用作妊娠动物的堕胎药。[1][3][4]阿来司酮也具有一些抗糖皮质激素活性。[5][6]
参考资料
- ^ 1.0 1.1 Kaufman LK, Baldwin CJ. Pregancy Loss in the Bitch and Queen. Bonagura JD, Twedt DC (编). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. 1 December 2013: 3009–. ISBN 978-0-323-22762-9.
- ^ Squires EJ. Endocrine manipulation of reproduction.. Applied Animal Endocrinology. CABI. 2010: 207–. ISBN 978-1-84593-755-3.
- ^ 3.0 3.1 Papich MC. Aglepristone. Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier Health Sciences. 3 November 2010: 120–. ISBN 978-1-4377-0192-0.
- ^ Fieni F, Martal J, Marnet PG, Siliart B, Bernard F, Riou M, Bruyas JF, Tainturier D. Concannon PW , 编. Hormonal variation in bitches after early or mid-pregnancy termination with aglepristone (RU534). Journal of Reproduction and Fertility. Supplement. Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000. 2001, 57: 243–8. ISBN 978-0-906545-37-9. PMID 11787157.
- ^ Batista M, Reyes R, Santana M, Alamo D, Vilar J, González F, et al. Induction of parturition with aglepristone in the Majorera goat. Reproduction in Domestic Animals = Zuchthygiene. October 2011, 46 (5): 882–888. PMID 21320179. doi:10.1111/j.1439-0531.2011.01759.x.
- ^ Baan M, Taverne MA, de Gier J, Kooistra HS, Kindahl H, Dieleman SJ, Okkens AC. Hormonal changes in spontaneous and aglépristone-induced parturition in dogs. Theriogenology. March 2008, 69 (4): 399–407. PMID 18054071. doi:10.1016/j.theriogenology.2007.10.008.
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